BIC - Publications - ICMR-NIRRCH

Molecular insights on the proangiogenic effects of VEGF like growth factor derived from horseshoe crab perivitelline fluid

2026

K. G. Aghila Rani, Hrishikesh Pandit, Rambhadur Subedi, Sayli Otiv-Pandit, Anil Bankati Jogdand, Hajra Gupta, Prayagraj Fandilolu, Sushama Rokade, Susan Idicula-Thomas, Anil Chatterji & Taruna Madan

Scientific Reports, 2026

https://doi.org/10.1038/s41598-025-32706-3

 

Predicting Toxicity of Insect Venom-Derived Antimicrobial Peptides Using MD Simulations: A Comparative Study of Multi-Component and Realistic Mammalian Membrane Models.

2025

Sekar, P. C., Gawde, U., Kumar, C., & Idicula-Thomas, S.

The Journal of membrane biology, 2025

https://doi.org/10.1007/s00232-025-00363-2

 

EpiCandIn: An open online resource for epidemiology of Candida infections in India

2024

Rahate, K., Arshi, A., Barai, R.S., Chakraborty, S., & Idicula-Thomas, S.

Indian Journal of Medical Research, 2024

https://10.25259/ijmr_886_23

 

Investigating role of positively selected genes and mutation sites of ERG11 in drug resistance of Candida albicans

2024

Fandilolu, P., Kumar, C., Palia, D., & Idicula-Thomas, S.

Archives of microbiology, 2024

https://doi.org/10.1007/s00203-024-04159-1

 

Relation of mitochondrial DNA copy number and variants with the clinical characteristics of polycystic ovary syndrome

2024

Thariyal, S P, Rasal, S, Gawde, U, Mukherjee, S, Patil, A, Joshi, B, Idicula-Thomas, S, & Shukla, P. 

Molecular and Cellular Endocrinology, 2024 https://doi.org/10.1016/j.mce.2024.112386

 

Differential proteomics of circulating extracellular vesicles of placental origin isolated from women with early-onset preeclampsia reveal aberrant innate immune and hemostasis processes

2024

Rao A, Subedi R, Kundu I, Idicula-Thomas S, Shinde U, Bansal V, Balsarkar G, Mayadeo N, Das DK, Balasinor N, Madan T.

Am J Reprod Immunol, 2024 https://doi.org/10.1111/aji.13860

 

PBITV3: A robust and comprehensive tool for screening pathogenic proteomes for drug targets and prioritizing vaccine candidates

2024

Chakraborty, S., Askari, M., Barai, R.S. and Idicula-Thomas S

Protein Sciences, 2024 https://doi.org/10.1002/pro.4892

 

Ferroptosis mediators vary in metabolic syndrome, type-2 diabetes, and hypercholesterolemia: A meta-analysis report

2023

Kundu I, Pande A, Das T, Idicula-Thomas S

Genes & Diseases, 2023 https://doi.org/10.1016/j.gendis.2023.06.024

 

Genomic and computational analysis of four novel variants of MPL gene in Congenital Amegakaryocytic Thrombocytopenia

2023

Shah A, Kumar C, Shanmukhaiah C, Rajendran A, Mudaliar S, Idicula-Thomas S & Vundinti B R

Annals of Hematology 2023 https://doi.org/10.1007/s00277-023-05347-7

 

Mammalian cysteine-rich secretory proteins interact with plasma membrane Ca2+ exporter PMCA4b

2023

Miya V, Kumar C, Breed AA, Idicula-Thomas S, Pathak BR

Andrology, 2023 https://doi.org/10.1111/andr.13549

 

FSHR activation through small molecule modulators: Mechanistic insights from MD simulations

2023

Kumar C and Idicula-Thomas S

Computers in Biology and Medicine, 2023, 106588, ISSN 0010-4825,https://doi.org/10.1016/j.compbiomed.2023.106588

 

N-Linked Glycosylation in Chinese Hamster Ovary Cells Is Critical for Insulin-like Growth Factor 1 Signaling

2022

Salvi R, Kumar C, Brahmbhatt K, Subedi R, Idicula-Thomas S, Madan T, Biswas B

International Journal of Molecular Sciences, 23, 14952. https://doi.org/ 10.3390/ijms232314952

 

Expanding the therapeutic options for Candida infections using novel inhibitors of secreted aspartyl proteases

2022

Chakraborty S, Rahate K, Kumar C, Idicula-Thomas S.

Drug Development Research, (2022)1– 14. https://doi.org/10.1002/ddr.22015

CAMPR4: a database of natural and synthetic antimicrobial peptides.

2022

Gawde U, Chakraborty S, Waghu F H, Barai R S, Khanderkar A, Indraguru R, Shirsat T, Idicula-Thomas S.

Nucleic Acids Research, 2023, Vol. 51, Database issue D377–D383, https://doi.org/10.1093/nar/gkac933

 

Human Surfactant Protein D Facilitates SARS-CoV-2 Pseudotype Binding and Entry in DC-SIGN Expressing Cells, and Downregulates Spike protein Induced Inflammation

2022

Beirag N, Kumar C, Madan T, Shamji M.H, Bulla R, Mitchell D, Murugaiah V, Neto M.M, Temperton N.J, Idicula-Thomas S and Varghese P.M.

Frontiers in Immunology, Volume 13, 2022, ISSN 1664-3224, https://doi.org/10.3389/fimmu.2022.960733

 

 

GeDiPNet: Online resource of curated gene-disease associations for polypharmacological targets discovery

2022

Kundu I, Sharma M, Barai R S, Pokar K, Idicula-Thomas S

Genes & Diseases. 2022 https://doi.org/10.1016/j.gendis.2022.05.034.

Pathway Analysis of Genome Wide Association Studies (GWAS) Data Associated with Male Infertility

2022

Salvi R, Gawde U, Idicula-Thomas S, Biswas B

Reproductive Medicine. 2022; 3(3):235-245. https://doi.org/10.3390/reprodmed3030018

Multimorbidity landscape of schizophrenia: Insights from meta-analysis of genome wide association studies

2022

Gawde U, Hegde P, Desai K, Barai R S, Shekhar B R, Das D K, Idicula-Thomas S

Schizophrenia Research, Volume 243, 2022, Pages 214-216, ISSN 0920-9964, https://doi.org/10.1016/j.schres.2022.03.013

Mapping of FSHR agonists and antagonists binding sites to identify potential peptidomimetic modulators

2022

Aathi M S, Kumar C, Prabhudesai K S, Shanmugarajan D, Idicula-Thomas S

Biochimica et Biophysica Acta (BBA) – Biomembranes, Volume 1864, Issue 4 (2022)

FSHR antagonists can trigger a PCOS-like state

2021

Waghu F H, Desai K, Srinivasan S, Prabhudesai K S, Dighe V, Venkatesh K V & Idicula-Thomas S

Systems Biology in Reproductive Medicine, (2021)

Human Properdin Released By Infiltrating Neutrophils Can Modulate Influenza A Virus Infection

2021

Mathews P, Mukherjee S Al-Mohanna F, Saleh S, Almajhdi F, Beirag N, Alkahtani S, Rajkumari R, Nal B, Sim R, Idicula-Thomas S, Madan T, Murugaiah V, Kishore U

Frontiers in Immunology. 12. 747654. (2021)

Comparison of machine learning algorithms applied to symptoms to determine infectious causes of death in children: national survey of 18,000 verbal autopsies in the Million Death Study in India

2021

Idicula-Thomas S, Gawde U & Jha P

BMC Public Health 21, 1787 (2021)

Central residues of FSHβ (89-97) peptide are not critical for FSHR binding: Implications for peptidomimetic design

2021

Prabhudesai KS, Raje S, Desai K, Modi D, Dighe V, Contini A, Idicula-Thomas S

Bioorg Med Chem Lett. 2021 Jul 15;44:128132 (2021)

Exploring the druggable proteome of Candida species through comprehensive computational analysis

2021

Shuvechha Mukherjee, Indra Kundu, Mehdi Askari, Ram ShankarBarai, K.V. Venkatesh, Idicula-Thomas S

Genomics Volume 113, Issue 2, March 2021, Pages 728-739 (2021)

Enrichment analyses of diseases and pathways associated with precocious puberty using PrecocityDB

2021

Sharma M, Kundu I, Barai RS, Bhaye S, Desa Ki, Pokar K and Idicula-Thomas S

Scientific Reports 11, 4203 (2021). https://doi.org/10.1038/s41598-021-83446-z

A Recombinant Fragment of Human Surfactant Protein D Binds Spike Protein and Inhibits Infectivity and Replication of SARS-CoV-2 in Clinical Samples

2021

Madan T, Biswas B, Varghese PM, Subedi R, Pandit H, Idicula-Thomas S, Kundu I, Rooge S, Agarwal R, Tripathi DM, Kaur S, Gupta E, Gupta SK, Kishore U

Am J Respir Cell Mol Biol. (2021) doi: 10.1165/rcmb.2021-0005OC. Epub ahead of print. PMID: 33784482

Collection of antimicrobial peptides database and its derivatives: Applications and beyond

2020

Waghu FH, Idicula-Thomas S

Protein Sci. 2020 Jan;29(1):36-42. doi: 10.1002/pro.3714

A QSAR modeling approach for predicting myeloid antimicrobial peptides with high sequence similarity

2020

Waghu FH, Gawde U, Gomatam A, Coutinho E, Idicula-Thomas S

Chem Biol Drug Des. 2020;10.1111/cbdd.13749. doi:10.1111/cbdd.13749

Identification and in vivo validation of a 9-mer peptide derived from FSHβ with FSHR antagonist activity

2020

Prabhudesai KS, Raje S, Dhamanaskar A. Modi D. Dighe V. Contini A. Idicula-Thomas S.

Peptides. 2020;132:170367. doi:10.1016/j.peptides.2020.170367

A steady-state modeling approach for simulation of antimicrobial peptide-cell membrane interaction

2020

Srinivasan S, Waghu FH, Idicula-Thomas S, Venkatesh KV.

Biochim Biophys Acta Biomembr. 2020;1862(4):183242. doi:10.1016/j.bbamem.2020.183242

Meta-analysis of gene expression profiles of lean and obese PCOS to identify differentially regulated pathways and risk of comorbidities

2020

Idicula-Thomas S, Gawde U, Bhaye S, Pokar K, Bader G D

Computational and Structural Biotechnology Journal

A 5-mer peptide derived from hinge region of hFSHR can function as positive allosteric modulator in vivo

2020

Prabhudesai KS, Aathi MS, Dighe V, Idicula-Thomas S

Biochimica et Biophysica Acta (BBA)-Biomembranes, 183492

PCOSKB_R2: a database of genes, diseases, pathways, and networks associated with polycystic ovary syndrome.

2020

Sharma, M, Barai, RS, Kundu, I, Bhaye S., Pokar K, Idicula-Thomas S

Sci Rep 10, 14738

Membrane Interactome of a Recombinant Fragment of Human Surfactant Protein D Reveals GRP78 as a Novel Binding Partner in PC3, a Metastatic Prostate Cancer Cell Line

2020

Thakur G, Sathe G, Kundu I, Biswas B, Gautam P, Alkahtani S, Idicula-Thomas S, Sirdeshmukh R, Kishore U, Madan T

Front Immunol. 2021 Jan 19;11:600660. doi: 10.3389/fimmu.2020.600660. PMID: 33542717

Discovery of small molecule binders of human FSHR(TMD) with novel structural scaffolds by integrating structural bioinformatics and machine learning algorithms

2019

Sahu B, Shah S, Prabhudesai K, Contini A, Idicula-Thomas S

J Mol Graph Model Jun;89:156-166. doi: 10.1016/j.jmgm.2019.02.001.

Effect of diversity in gp41 membrane proximal external region of primary HIV-1 Indian subtype C sequences on interaction with broadly neutralizing antibodies 4E10 and 10E8

2019

Sutar J, Padwal V, Sonawani A, Nagar V, Patil P, Kulkarni B, Hingankar N, Deshpande S, Idicula-Thomas S, Jagtap D, Bhattacharya J, Bandivdekar A, Patel V.

Virus Res. 2019 Nov;273:197763. doi: 10.1016/j.virusres.2019.197763.

Designing Antibacterial Peptides with Enhanced Killing Kinetics

2018

Waghu FH, Joseph S, Ghawali S, Martis EA, Madan T, Venkatesh KV, Idicula- Thomas S

Front Microbiol. 2018 Feb 23;9:325. doi: 10.3389/fmicb.2018.00325

Evaluation of 4-thiazolidinone derivatives as potential reverse transcriptase inhibitors against HIV-1 drug resistant strains.

2017

Suryawanshi R, Jadhav S, Makwana N, Desai D, Chaturbhuj D, Sonawani A, Idicula-Thomas S, Murugesan V, Katti SB, Tripathy S, Paranjape R, Kulkarni S

Bioorg Chem. 2017, 71:211-218, doi: 10.1016/j.bioorg.2017.02.007.

Protein-Protein interaction between surfactant protein D and DC-SIGN via C-type lectin domain can suppress HIV-1 transfer.

2017

Dodagatta-Marri E, Mitchell DA, Pandit H, Sonawani A, Murugaiah V, Idicula-Thomas S, Nal B, Al-Mozaini MM, Kaur A, Madan T, Kishore U.

Front Immunol 31: 8:834, doi: 10.3389/fimmu.2017.00834, 2017.

PBIT: Pipeline builder for identification of drug targets for infectious diseases.

2017

Shende G, Haldankar H, Barai RS, Bharmal MH, Shetty V, Idicula-Thomas S.

Bioinformatics 33: 929-931, 2017