Scientist F
Email: patila@nirrch.res.in
Phone: +(91-22)24192028
Department: Department of Clinical Research
Research Interests
- Polycystic Ovary Syndrome (PCOS)
- Infertility
- Maternal and child health
Academic Background
| Degree | Institution | Field(s) | Year |
| MD | Seth G.S.Medical College, KEM Hospital, Mumbai | Obstetrics & Gynecology | 2003 |
| DGO | Seth G.S.Medical College, KEM Hospital, Mumbai | Obstetrics & Gynecology | 2003 |
| MBBS | Seth G.S.Medical College, KEM Hospital, Mumbai | — | 1997 |
Professional Experience
| SR No | INSTITUTION/PLACE | DESIGNATION | FROM | TO |
| 1 | Pre-PG State Govt Primary Health Centre, Furus, Ratnagiri | Medical Officer | 1999 | 2000 |
| 2 | Seth G.S.Medical College, KEM Hospital, Mumbai | Post Graduation M.D (Obstetrics & Gynaec) | 2000 | 2003 |
| 3 | Seth G.S.Medical College,KEM Hospital, Mumbai | Registrar (MD qualified) | 2003 | 2004 |
| 4 | Medical Officer | Mumbai Port Trust Hospital | 2004 | 2004 |
| 5 | Research Officer (Medical) | National Institute For Research in Reproductive Health (NIRRH) on Project “Development of National Guidelines for RTIs/STIs at PHC level” (funded by WHO) | 2005 | 2006 |
| 6 | Lecturer (Assistant Professor) (Obs & Gynaec) |
Lokmanya Tilak Municipal Medical College, Lokmanya Tilak Municipal General Hospital, Sion, Mumbai | 2006 | 2008 |
| 7 | Scientist “B” | ICMR National Institute For Research in Reproductive Health (NIRRH), Mumbai | 2009 | 2012 |
| 8 | Scientist “C” | ICMR -NIRRH, Mumbai | 2012 | 2016 |
| 9 | Scientist “D” | ICMR -NIRRH, Mumbai | 2016 | 2019 |
Present
| Name | Designation |
| Dr Manju Sanilkumar | Senior Research Fellow |
Past
| Name | Designation | From | To |
| Dr Anshu Verma | Consultant Gynecologist | April 2019 | July 2019 |
| Dr Ruffiyat Kazi | Consultant Gynecologist | Sep 2019 | Dec 2019 |
| Dr Prachi Dalvi | Yoga Instructor | May 2019 | Jan 2020 |
| Dr Vidhya Chavan | Project Technical Officer | Dec 2019 | August 2020 |
| Shila Kachara | Project ANM | Dec 2019 | August 2020 |
| Dr Aishvarya Karandikar | Project Technical Officer | March 2021 | May 2021 |
| Ganaga Bhekare | Project ANM | March 2021 | Oct 2022 |
| Dr Sonu S. Babu | Project Technical Officer | August 2021 | Feb 2022 |
| Dr Sayantika Kumari | Project Technical Officer | July 2022 | Oct 2022 |
| Dr Hrishikesh Munshi | Scientist B | Jan 2021 | Oct 2021 |
| Dr Ruffiyat Kazi | Scientist B | Dec 2019 | March 2020 |
| Prachi Joshi | Data Entry Operator | Oct 2019 | Oct 2020 |
| Radhika Mhatre | Senior Research Fellow | Dec 2019 | Sept 2020 |
| Dr Mangalam Vardha | Senior Research Fellow | June 2021 | Dec 2022 |
Publications
Correlation between sperm DNA fragmentation and methylation in male partners of couples with idiopathic recurrent pregnancy loss.
2024
Incidence and Correlates of Maternal Near Miss (MNM) Events in Tertiary hospitals of Maharashtra state, India: A Prospective Observational study
2024
Ragini Kulkarni, Sanjay Chauhan, Juzar Fidwi , Arun Nayak , Anil Humane , Rahul Mayekar , Shahina Begum , Anushree Patil and Niranjan Mayadeo
Indian J Med Res 158, July 2023, 70-78
https://doi.org/10.4103/ijmr.ijmr_2932_21
DNA methylation biomarkers to identify epigenetically abnormal spermatozoa in male partners from couples experiencing recurrent pregnancy loss.
2023
Mapping the vaginal microbiota variations in women from a community clinic in Mumbai,India.
2023
Assessment of Health-Related Quality of Life Using PCOSQ Tool, Its Determinants and Coping Mechanisms Used by Women with Polycystic Ovarian Syndrome Attending Multidisciplinary Clinic in Mumbai, India.
2023
Molecular characterization of variants in mitochondrial DNA encoded genes using next generation sequencing analysis and mitochondrial dysfunction in women with PCOS
2023
Characterization of peripheral T helper 17 (Th17) cells phenotype in postmenopausal women with estrogen insufficiency.
2023
Association of OPG and RANKL gene polymorphisms with bone mineral density in Indian women
2022
Evaluation of cytokine profile in cervicovaginal lavage specimens of women having asymptomatic reproductive tract infections.
2022
Enablers & challenges of tribal women & health system for implementation of screening of non-communicable diseases & common cancers: A mixed-methods study in Palghar district of Maharashtra, India.
2022
Community perceptions and treatment seeking behaviour for infertility in India: A qualitative research study.
2022
Association of AMH and AMHR2 gene polymorphisms with ovarian response and pregnancy outcomes in Indian women
2022
Whole genome bisulfite sequencing of sperm reveals differentially methylated regions in male partners of idiopathic recurrent pregnancy loss cases.
2022
Facilitators & barriers for effective implementation of Dakshata programme to improve the quality of institutional maternal care in tribal blocks of Maharashtra.
2022
An integrated multidisciplinary model of care for addressing comorbidities beyond reproductive health among women with polycystic ovary syndrome in India.
2022
Opposing roles for sMAdCAM and IL-15 in COVID-19 associated cellular immune pathology
2022
Singh AK, Kasarpalkar N, Bhowmick S, Paradkar G, Talreja M, Shah K, Tiwari A, Palav H, Kaginkar S, Kulkarni R, Patil A, Kalsurkar V, Agrawal S, Shastri J, Dere R, Bharmal R, Mahale SD, Bhor VM, Patel V. Opposing roles for sMAdCAM and IL-15 in COVID-19 associated cellular immune pathology.
Cross sectional study to evaluate microbiological spectrum of RTI/STI and co-infections among women with cervicitis or cervico-vaginitis from a community clinic in Mumbai.
2022
Effect of Vitamin D deficiency on the metabolic profile of women with Polycystic Ovary Syndrome
2022
Dysregulated serum and seminal plasma levels of surfactant protein D and MCP-1 in men with genital tract infection/inflammation.
2022
Maternal near miss events in India
2021
DNA methylation defects in spermatozoa of male partners from couples experiencing recurrent pregnancy loss.
2021
Elucidating the impact of obesity on hormonal and metabolic perturbations in polycystic ovary syndrome phenotypes in Indian women
2021
Effect of Vitamin D Levels on Bone Remodeling in Healthy Women
2020
Female genital tuberculosis in light of newer laboratory tests: A narrative review.
2020
Identification of Variants in Mitochondrial D-Loop and OriL Region and Analysis of Mitochondrial DNA Copy Number in Women with Polycystic Ovary Syndrome.
2020
An Update on Prevalence, Diagnosis, Treatment and Emerging issues of Genital Mycoplasma infection in Indian women: A Narrative Review
2019
Perspectives of Primary Health Care Providers on Implementing Cancer Screening Services in Tribal block of Maharashtra, India.
2019
Impact of training on awareness and knowledge of Service Providers about Maternal Near Miss Events in Maharashtra, India
2019
Consensus statement on the use of oral contraceptive pills in polycystic ovarian syndrome women in India.
2018
Capacity Assessment of District Health System in India on Services for Prevention and Management of Infertility.
2018
PON1 promoter polymorphisms contribute to PCOS susceptibility and phenotypic outcomes in Indian women.
2018
Simultaneous estimation of plasma levels of bisphenol-a and phthalate metabolites in fertile and infertile women by gas chromatography–mass spectrometry: method development, validation and troubleshooting.
2018
Preterm birth among pregnancies conceived by assisted reproduction techniques in Mumbai, Maharashtra, India.
2018
Visceral adiposity index among young girls with PCOS and its association with phenotypes and metabolic risk
2018
Yoga Therapy: The Fourth Dimension in the Multidisciplinary Management of Women with Polycystic Ovary Syndrome, A Narrative Review.
2018
Yoga Therapy: The Fourth Dimension in the Multidisciplinary Management of Women with Polycystic Ovary Syndrome, A Narrative Review
2017
LINE1 CpG-DNA Hypomethylation in Granulosa Cells and Blood Leukocytes is Associated with PCOS and Related Traits.
2017
Surfactant protein D induces immune quiescence and apoptosis of mitogen-activated peripheral blood mononuclear cells
2016
A Prospective Observational Study of ‘Near Miss’ Obstetric Events in Two Tertiary Hospitals of Mumbai, Maharashtra, India
2016
Prospective observational study of near-miss obstetric events at two tertiary hospitals in Mumbai, Maharashtra, India
2016
Serum levels of pHSP27 are associated with BMD in premenopausal and postmenopausal Indian women
2016
Influence of bone mineral density measurement on fracture risk assessment tool (FRAX®) scores in postmenopausal Indian women
2016
Is testing of menstrual blood justifiable for diagnosis of endometrial Tuberculosis among infertile women?
2015
Surfactant protein D induces immune quiescence and apoptosis of mitogen-activated peripheral blood mononuclear cells
2015
Monocyte proteomics reveals involvement of phosphorylated HSP27 in the Pathogenesis of Osteoporosis
2015
PON1 polymorphisms are associated with PCOS susceptibility, related traits and PON1 activity in Indian women with polycystic ovary syndrome
2015
A cross sectional study of Polycystic Ovarian Syndrome (PCOS) among adolescent and young girls in Mumbai, India
2014
Surfactant protein D inhibits HIV-1 infection of target cells via interference with gp120-CD4 interaction and modulates pro-inflammatory cytokine production
2014
Prevalence of HIV in unregistered hospital deliveries in western India
2013
Methylation analysis of idiopathic recurrent spontaneous miscarriage cases reveals aberrant imprinting at H19 ICR in normozoospermic individuals
2011
Projects Ongoing
| Project title | Funding agency | From | To |
| Centre for Product Development | ICMR | 2019 | 2024 |
| Prospective evaluation of etiological factors, trajectory of comorbidities and, efficacy and safety of various therapeutic agents among Indian women with Polycystic ovary syndrome (PCOS): A Multicentric ICMR-PCOS Cohort Study Phase II | ICMR | 2023 | 2028 |
Projects Completed
| Project title | Funding agency | From | To |
| Improving access for screening of common cancers and non-communicable diseases among women in tribal block of Maharashtra: Challenges in implementation | ICMR | 2019 | 2022 |
| Implementation of the Dakshata program to improve the quality of institutional deliveries in a tribal block of Maharashtra | ICMR | 2020 | 2021 |
| Effect of Yoga on physical and emotional health of infertile women with Polycystic Ovary Syndrome (PCOS) | DST | 2019 | 2023 |
| Retrospective data analysis of records of Multidisciplinary PCOS Clinic at ICMR-NIRRH, Mumbai. | Intramural | 2018 | 2022 |